Desmoplastic Mesothelioma: What You Need to Know

Desmoplastic Mesothelioma: What You Need to Know

Mesothelioma is a rare form of cancer that affects the lining of the lungs, abdomen, or heart. It is caused by exposure to asbestos, a fibrous mineral that was commonly used in construction and manufacturing in the 20th century. One of the less common types of mesothelioma is desmoplastic mesothelioma, which accounts for only 5-10% of all cases. In this article, we will explore what desmoplastic mesothelioma is, its causes and symptoms, and how it is diagnosed and treated.

What is Desmoplastic Mesothelioma?

Desmoplastic mesothelioma is a subtype of mesothelioma that is characterized by the presence of dense fibrous tissue, also known as desmoplasia. This tissue can make it difficult to diagnose the cancer, as it can mimic other benign conditions like fibrous pleurisy. Because of this, desmoplastic mesothelioma is often diagnosed at a later stage when the cancer has already spread.

Causes and Risk Factors

As with all types of mesothelioma, exposure to asbestos is the primary cause of desmoplastic mesothelioma. Asbestos was widely used in construction and manufacturing industries until the late 1970s, when its harmful effects became well-known. Exposure can occur through inhalation or ingestion of asbestos fibers, which can become lodged in the lining of the lungs or abdomen, causing irritation and inflammation that can lead to cancer.

Other risk factors for mesothelioma include:

- Working in industries that use asbestos
- Living with someone who has been exposed to asbestos
- Smoking, which can increase the risk of developing mesothelioma in those who have been exposed to asbestos

Symptoms of Desmoplastic Mesothelioma

The symptoms of desmoplastic mesothelioma can be similar to those of other types of mesothelioma, as well as other less serious conditions. Some common symptoms include:

- Shortness of breath
- Chest pain
- Persistent cough
- Fatigue
- Unexplained weight loss
- Swelling in the limbs

Because these symptoms can be attributed to other conditions, it is important to consult a doctor if you have been exposed to asbestos. Early detection can improve the chances of successful treatment.

Diagnosis of Desmoplastic Mesothelioma

Diagnosing desmoplastic mesothelioma can be challenging, as the dense fibrous tissue can be difficult to distinguish from other benign conditions. Imaging tests like X-rays, CT scans, and MRIs can help identify abnormalities in the lining of the lungs or abdomen, but a biopsy is typically necessary to confirm the diagnosis.

Treatment Options for Desmoplastic Mesothelioma

Treatment options for desmoplastic mesothelioma depend on the stage of the cancer, as well as the patient's overall health. Some common treatment options include:

- Surgery: Surgical removal of the affected tissue may be recommended for some patients, especially if the cancer is localized and has not spread to other parts of the body.
- Chemotherapy: Chemotherapy drugs can help kill cancer cells and slow the progression of the disease.
- Radiation therapy: Radiation can be targeted to specific areas of the body to kill cancer cells and reduce symptoms.

Clinical trials and experimental treatments may also be available for patients who do not respond to traditional treatments or who have advanced-stage cancer.

Living with Desmoplastic Mesothelioma

Living with desmoplastic mesothelioma can be challenging, as the disease can be difficult to treat and may cause a range of symptoms. However, there are resources available for patients and their families, including support groups, counseling, and financial assistance programs. It is also important to maintain a healthy lifestyle, get plenty of rest, and manage stress through activities like meditation or yoga.


Desmoplastic mesothelioma is a rare but aggressive form of cancer that can be difficult to diagnose and treat. However, with early detection and proper treatment, patients can improve their chances of survival and manage their symptoms. If you have been exposed to asbestos or are experiencing symptoms of mesothelioma, consult a doctor as soon as possible to receive a proper diagnosis and explore your treatment options.