Mesothelioma clinical trials: Understanding your options

Mesothelioma Clinical Trials: Understanding Your Options

When it comes to mesothelioma, a rare and aggressive form of cancer, conventional treatments like surgery, chemotherapy, and radiation can only do so much. That's why clinical trials often provide hope for patients, as they test new treatments that may be more effective in fighting this deadly disease. If you or a loved one has been diagnosed with mesothelioma, it's important to understand the different types of clinical trials available and how they can benefit you.

What Are Mesothelioma Clinical Trials?

Mesothelioma clinical trials are research studies that investigate new treatments or ways to prevent, detect, or manage mesothelioma. These trials can test a variety of approaches, from new drugs and combinations of treatments to different ways of administering treatment and diagnostic techniques. Clinical trials are typically conducted in phases, with each phase designed to answer a specific research question and determine the safety, tolerability, and efficacy of the treatment being tested. The phases are:
  • Phase 1: Tests the safety and dosage of a new treatment in a small group of patients.
  • Phase 2: Tests the effectiveness of the treatment in a larger group of patients.
  • Phase 3: Compares the new treatment to the standard treatment in a randomized controlled trial.
  • Phase 4: Monitors the long-term safety and effectiveness of the treatment after it has been approved by the FDA.

Why Participate in a Mesothelioma Clinical Trial?

Participating in a mesothelioma clinical trial can provide several benefits, including:
  • Access to new, experimental treatments that may be more effective than standard treatments
  • Access to a team of medical professionals and researchers who specialize in mesothelioma
  • The opportunity to contribute to the advancement of mesothelioma research and help future patients
  • Extra medical attention and care during the trial

How to Find Mesothelioma Clinical Trials

There are several resources available to help you find mesothelioma clinical trials, including:
  • Your doctor or oncologist may be aware of ongoing trials and can provide you with information
  • Cancer centers and research institutions often list ongoing trials on their websites
  • The National Cancer Institute's Clinical Trials database lists clinical trials for mesothelioma and other types of cancer
  • The Mesothelioma Applied Research Foundation also provides information on ongoing trials

Considerations Before Participating

Before you decide to participate in a mesothelioma clinical trial, it's important to consider several factors, including:
  • The potential risks and benefits of the treatment being tested
  • The length and schedule of the trial
  • Travel and lodging costs, as some trials may be located far from your home
  • Insurance coverage and out-of-pocket expenses
It's also important to note that participation in clinical trials is voluntary, and you have the right to withdraw at any time.


Mesothelioma clinical trials offer hope for patients and are critical to advancing our understanding and treatment of this rare and deadly cancer. By understanding your options and considering the potential risks and benefits, you can make an informed decision about whether to participate in a clinical trial. Talk to your doctor or oncologist, explore the resources available, and take an active role in your mesothelioma treatment.